Guided Therapeutics

This core is dedicated to the development and testing new technologies in imaging merged with developing and applying new physical therapies such as laser, photodynamic therapy, and high intensity focused ultrasound.  Another key area of guided therapeutics is on the operating room.  The integration of imaging technologies can provide a “GPS” for surgeons – where surgical tools, the surgical target and the surrounding anatomy are visualized precisely in real time three-dimensional images. Image-guided technology allows the surgeon to accurately pinpoint diseased tissue and remove them without harming the surrounding structures. Patients benefit from faster recovery times and enhanced quality of life during and after treatment. It also reduces the likelihood that a patient would have to return for further surgery. This core will be instrumental in the care of cancer, cardiac, and neurology patients.

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Faculty Members Associated with this Core

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    Director, Techna Institute, Interim Co-lead, Guided Therapeutics; Head, Radiation Physics, Princess Margaret Hospital; Senior Scientist, Ontario Cancer Institute;
    Dr. David Jaffray graduated from the University of Alberta, Edmonton, Alberta, Canada with a B.Sc. in Physics (Hons.) in 1988 and completed his Ph.D. in the Department of Medical Biophysics at the University of Western Ontario, London, Ontario in 1994. Following graduation, he took a position as Staff Physicist in the Department of Radiation Oncology at William Beaumont Hospital, Royal Oak, Michigan where he instigated a direction of research that garnered funding from the NIH and from congressionally-directed funding programs. Dr. Jaffray became a Board Certified Medical Physicist (ABMP – Radiation Oncology) in 1999. In 2002, Dr. Jaffray joined the Princess Margaret Hospital in Toronto, Ontario as Head of Radiation Physics and a Senior Scientist within the Ontario Cancer Institute. Dr. Jaffray holds the Fidani Chair in Radiation Physics and is a principal in the STTARR Innovation Centre of the University Health Network. He is appointed as a Professor in the Departments of Radiation Oncology, Medical Biophysics, and Institute for Biomaterials and Biomedical Engineering at the University of Toronto. His primary area of research over the past 10 years has been in the development and application of image-guided radiation therapy. He has over 5 patents issued and several licensed, including, kilovoltage cone-beam computed tomography for image-guided radiation therapy. Dr. Jaffray has in excess of 120 peer-reviewed publications in the field, in excess of 100 invited lectures, and holds numerous peer-review and industry sponsored research grants. He sits on numerous scientific and research boards and has contributed to the NIH and CIHR grant review process for several years. He is a member at large of the Science Council of the AAPM and has an active teaching role in workshops and annual meeting of the American Society of Therapeutic Radiation Oncology (ASTRO). He has an active interest in commercialization and led the development of a variety of commercial products including software and hardware for QA and the development of small animal irradiator systems for basic research. He has successfully supervised over 20 graduate students and fellows. Dr. Jaffray has won each of the major prizes in the field of the medical physics, including, the Sylvia Sorkin-Greenfield Award, The Farrington Daniels Award, and the Sylvia Fedoruk Award. In 2004, Dr. Jaffray was identified as one of Canada’s Top 40 Under 40 and was recognized by The University of Western Ontario with their Young Alumni Award. His current research interests focus on the development of novel approaches of targeting and applying radiation therapy and translating these advances to clinical practice.
    active 3 days, 10 hours ago
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    Co-lead, Guided Therapeutics, Techna Institute; Professor, University of Toronto; Head, Surgical Services, Princess Margaret Hospital; Chief, Department of Surgical Oncology, University Health Network and Mount Sinai Hospital; Provincial Head, Surgical Oncology Program, Cancer Care Ontario
    Dr. Irish graduated with his M.D. degree in 1984 from the University of Toronto. He completed residency training at UCLA and at the University of Toronto. He completed his Master’s of Science degree under the supervision of Dr Alan Bernstein where he studied molecular biology of head and neck malignancies. He completed the American Head and Neck Society fellowship in head and neck oncology in 1991 and joined the staff of the University Health Network in 1992. He is currently Chief of the Department of Surgical Oncology at the Princess Margaret Hospital/University Health Network and Mt. Sinai Hospital, Toronto, and is full Professor of Otolaryngology-Head and Neck Surgery at the University of Toronto. He is Lead, Access to Care and Strategic Funding Initiatives for the Surgical Oncology Program at Cancer Care Ontario and is responsible for the Cancer Surgery Wait Times portfolio. Dr. Irish focuses primarily on head and neck oncology and surgical reconstruction of the head and neck region. His research interests range from basic science studies in head and neck cancer to patient education intervention trials to outcome studies in head and neck cancers. More recently he has headed a multidisciplinary program in Guided Therapeutics at UHN. He has over 160 peer review publications and over 20 book chapters and has over $2M in peer review funding for his research through the NCIC and CIHR.
    active 6 months, 1 week ago