Topic: Digital Microfluidics for Clinical Application
Join us for Techna Rounds as we welcome Associate Professor Aaron Wheeler to be our speaker for the month. Aaron Wheeler completed his Ph.D. at Stanford in 2003. He then spent two years as a postdoctoral fellow at UCLA, and since 2005, he has been the Canada Research Chair of Bioanalytical Chemistry at the University of Toronto. Dr. Wheeler’s research interests range broadly from clinical analysis to cell-based assays to proteomics, with a central theme of developing microfluidic tools to solve laboratory problems. Dr. Wheeler is fortunate to work with a creative, prolific research group, whose success has led to international recognition including the Arthur F. Findeis Award from the American Chemical Society and the Joseph Black award from the Royal Society of Chemistry.
Digital microfluidics is a fluid-handling technique in which droplets are manipulated by electrostatic forces on an array of electrodes coated with a hydrophobic insulator. Digital microfluidics is complementary to the more common format of microchannel-based fluidics, with the former being uniquely well-suited for managing many different reagents in parallel, fluidic operations involving solids, and for preparative-scale applications. This talk will cover my group’s recent work applying digital microfluidics to problems in clinical sample analysis including the quantification of analytes associated with breast cancer in tissue and for screening newborn samples for markers associated with metabolic disorders.
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