Cyclotron and Radiochemistry Laboratory
Operational since 2014 the UHN Cyclotron & Radiochemistry Laboratory is part of the joint venture CanProbe with the Center for Probe Development & Commercialization. A dedicated laboratory for research, development, and production of new PET imaging agents – its mission is to enable all imaging research requiring radiotracers to have access to them.
The facility is working with academic researchers, clinician scientists, and industrial partners to develop the next generation radiopharmeuticals. These tracers can be used to detect and visualize cancer, as well as cardiac or neural diseases and the effectiveness of new treatments such as stem cell transplantation amongst many other applications. The facility is now supplying imaging agents to 15 active clinical trials throughout the GTA.
The guided therapeutics laboratory, located on the 7th floor of the Toronto Medical Discovery Tower, is a collaborative space that combines innovative science and technology to catalyze new image guided applications. The multi-disciplinary environment enables rapid prototyping and translation of applications from preclinical to clinical stage under scientific, engineering, and clinical expertise.
There applications integrate technologies such as computer vision, computer graphics, augmented reality, multi-modality imaging, molecular agents, navigation, and robotics. Clinical application domains include head and neck surgery, thoracic surgery, orthopedic surgery, radiation therapy, and intervention radiology.
GTx OR (Guided Therapeutics Operating Room) is a dedicated research OR located within the existing Toronto General Hospital surgical hub for cost-effective support/integration and is equipped with image-based surgical navigation technologies (x-ray and optical navigation; visualization).
This advanced OR is designed to ensure the rapid implementation of novel of image guided technologies for the benefit of patients. The GTx OR is the first facility in the world that has a dual energy Siemens Definition FLASH CT scanner and a state-of-the-art robotic C-arm, the Siemens Artis Zeego, within the same OR.
Healthcare Human Factors
Healthcare Human Factors is the largest Human Factors team dedicated to healthcare internationally. Acting as consultants, researchers, designers and evaluators, we are setting standards and developing best practices for human factors in healthcare, leading cultural change and making an impact locally and worldwide. We employ user-centered design methods and our deep understanding of the medical field to create impact in research, design and evaluation.
Located within one of the largest academic health science centres in the world at University Health Network, we are embedded in the healthcare setting with access to clinical users and patients that we design, test and create for. We have state-of-the-art usability testing facilities geared for healthcare and attract private and public sector clients including hospitals, the Ministry of Health and Long-Term Care (MOHLTC), Ontario Medical Association (OMA) and Canada Health Infoway (CHI)
Our mission is to improve healthcare for people through safe, usable and effective technologies and processes.
Our vision is a healthcare system that at every stage in its process is informed by human factors principles.
OpenLab at UHN, located at Toronto General Hospital, is a multi-disciplinary service design and innovation centre dedicated to developing solutions to complex problems that improve both the process and experience of care. OpenLab brings together patients, clinicians, engineers, social scientists, designers and business people to understand health system issues from multiple perspectives.
It uses design thinking to uncover the needs, behaviors and desires of users, and develops solutions that stress real-world effectiveness, adoption and sustainability.
Lead by Dr. Patrick Veit-Haiback, from the Joint Department of Medical Imaging and the Department of Medical Imaging at the University Health Network, the PET/MR Facility features a Siemens Biograph mMR – an integrated whole-body PET and high-field 3T MRI system. Strategically located adjacent to the Cyclotron & Radiochemistry Laboratories, this state-of-the-art system enables the study of metabolism and pathophysiology at the molecular level with simultaneous spatial localization of metabolites. This system takes advantage of the superior soft-tissue contrast capabilities of MR, when compared, to CT.
Access to the facility is open to internal and external academics and clinician-scientists and industry to support all levels of research. There are currently 14 active trials using the equipment. For more information about the facility contact Dr. Veit-Haiback at Patrick.Veit-Haibach@uhn.ca.
The Magnetic Resonance guided Radiation Therapy (MRgRT) suite consists a 1.5T open bore MR imaging scanner on rails that moves between a linear accelerator and a High Dose Rate (HDR) brachytherapy suite. The only one of its kind in the world the suite has been treating patients since 2014.
The suite allows for MR imaging, which has superior soft-tissue contrast to current cone-beam CT system used for image-guided radiation therapy, to be completed at the time of intervention with minimum disruption to the patient and interventional team. MR-guided localization, motion assessment, targeting and monitoring of disease and normal structures can be completed at an unprecedented level of precision and accuracy.
The MRgRT is enabling the development of new radiotherapy techniques such as adaptive radiotherapy and MR guided robotic interventions.
NanoMed Fab Facility
Nanotechnologies are emerging rapidly as critical new enablers in translating biological discoveries into medicine. Nanoscale constructs could serve as personalized nanomedicine for imaging and therapy of a wide range of diseases especially cancer. The NanoMed Fab Center, is funded by the Canada Foundation for Innovation and Ontario Research Fund to support and accelerate the overall vision of filling critical innovation gap between ‘making’ and ‘using’ targeted nanoparticles.
The Center provides a fully integrated nanomedicine platform—unique in Canada—to fabricate a spectrum of nanoparticles with targeting and pharmacokinetic properties designed for clinical use; to evaluate and validate these nanoparticles in relevant preclinical disease models; to produce and test small scale clinical-grade materials under GMP/GLP regulations.
For more information including available equipment and facilities and contact information click here: http://www.nanomedfab.com.